Technical guides covering autoclave design, scale-up criteria, WFI systems design, and process safety barriers.
Instrumentation Process Data Sheet (IPDS), Instrument Count & Technology Selection Guide: Pharma API & Chemical Plant Engineering
PID Loop Troubleshooting: 8 Root Causes of Poor Performance
An authoritative engineering guide on statistical process validation under FDA Stage 2 Process Performance Qualification (PPQ). Covers Cpk vs Ppk mathematical derivations, within-batch vs overall variance, tolerance interval batch number sizing (95/95 rule), and Box-Cox data transformations.
The technical articles, chemical engineering equations, and recommendations published in these blogs are for informational and educational purposes only. They are based on general engineering practices and principles, which may not apply to specific design contexts or plant conditions. Users are responsible for verifying all design criteria and safety margins with certified professional engineers prior to implementation.